Protecting the Achilles heel: three FolE_I-type GTP-cyclohydrolases needed for full growth of metal-resistant <i>Cupriavidus metallidurans</i> under a variety of conditions.

The exception was a barely significant decrease of reporter activity of the folE_IB1-lacZ fusion in the presence of dipyridyl (31% decrease, D = 1.12).

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At n = 4, significance is ≥97.5%; at n = 5, ≥99% (significant); and at n = 8, ≥99.9% (highly significant).

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