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Correlations between multimodal neuroimaging and peripheral inflammation in different subtypes and mood states of bipolar disorder: a systematic review.

Int J Bipolar Disord · 2024 · PMC10884387 · PMID 38388844

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an increasing trendno p-value reported
Remarkably, strong evidence from a longitudinal study further indicated an increasing trend in hippocampal volume and neurotrophic factor levels in patients on long-term lithium treatment (Inal-Emiroglu et al. 2015 ) since lithium can attenuate central nervous system damage and ameliorate affective symptoms through neurotrophic factor-mediated neuroprotection.

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