Relationship between the Expression of CHK2 and p53 in Tumor Tissue and the Course of Papillary Thyroid Cancer in Patients with <i>CHEK2</i> Germline Mutations.

Prognostically Favorable and Predictive Results Defined as Categories of Interest in Groups of PTC Patients with and without CHEK2 Mutations In the analyses described above, the associations between clinicopathological features (tumor diameter, papillary cancer histologic variant, vascular invasion, and age), response to therapy, and final follow-up and CHK2 expression, TP53 gene copy number, p53 expression, and p53 expression together with TP53 gene copy number were either statistically significant or borderline significant.

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We decided to examine further the associations that were significant or marginally significant.

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