Two-Year Results of 0.01% Atropine Eye Drops and 0.1% Loading Dose for Myopia Progression Reduction in Danish Children: A Placebo-Controlled, Randomized Clinical Trial.

When comparing the two-year overall progression in our placebo group and 0.01% (0.57 mm and 0.47 mm, respectively), it translates to a moderate treatment effect of an 18% reduction in AL progression in the 0.01% group compared to placebo, which is clinically relevant and is in line with the borderline significant one-year treatment effect we found in the 0.01% group in our previous interim analysis [ 24 ].

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