Immune signature of Chlamydia vaccine CTH522/CAF®01 translates from mouse-to-human and induces durable protection in mice.

Measuring the area under the curve (AUC) for mice proceeding to PID17 (PID3-PID17) ( n = 31) demonstrated a highly significant reduction in IFU in CTH522/CAF®01 vaccinated mice compared to control mice (Mann–Whitney U test, p < 0.0001) (Fig. 6f ).

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