In comparison to the 1 BV sample volume, there was no significant difference in haemagglutinin recovery when the sample loading volume continued to increase to 1.75 BV ( p > 0.05), with a decreasing trend in impurity removal (total protein removal: 3.74%; DNA removal: 4.33%).
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Enhanced Downstream Processing for a Cell-Based Avian Influenza (H5N1) Vaccine.
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