The Shifting Epidemiology of Hepatitis A in the World Health Organization Western Pacific Region.

In 2022 the WHO updated a position paper on Hepatitis A vaccine, which recommends that vaccination against hepatitis A virus be introduced into national immunization schedules for individuals aged ≥12 months, if indicated on the basis of: (i) an increasing trend over time of acute hepatitis A disease, including severe disease, among older children, adolescents or adults; (ii) changes in the endemicity from high to intermediate; and (iii) considerations of cost–effectiveness [ 110 ].

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In the face of a decreasing trend in hepatitis A in China since the introduction of the hepatitis A vaccine, outbreaks of hepatitis A continued to be reported as the most frequent cause of acute hepatitis.

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