A pilot investigation of the association between HIV-1 Vpr amino acid sequence diversity and the tryptophan-kynurenine pathway as a potential mechanism for neurocognitive impairment.

Virol J · 2024 · PMC10893664 · PMID 38395987

Europe PMC DOI

hedged sentence

0.0230

closest p · 0.5× alpha

0.0230

boldest claim

The sentences

nearing significancep =.023actually significant

After applying Bonferroni corrections ( p =.05/3) and adjusting for covariates (age and sex), only the Vpr G41 and A55 groups was nearing significance for higher levels of QUIN compared to the Vpr S41 and T55 groups, respectively (all p =.023).

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