Development of the gut microbiota in the first 14 years of life and its relations to internalizing and externalizing difficulties and social anxiety during puberty.

Disperse Puberty_2 samples at age 14 showed significantly more internalizing behavior at the same age without accounting for covariates (estimate = 0.4 and adjusted p = 0.02), while the difference became marginally insignificant after considering covariates (estimate = 0.3 and adjusted p = 0.079).

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