Inhibition of Aurora Kinase Induces Endogenous Retroelements to Induce a Type I/III IFN Response via RIG-I.

We observed that enrichment of the hallmark IFNα gene set was highly significant in most cell lines, and did not clearly track with microsatellite instability or Ras mutation status; although WT p53 was associated with all but HT-29.

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