The kynurenine and serotonin pathway, neopterin and biopterin in depressed children and adolescents: an impact of omega-3 fatty acids, and association with markers related to depressive disorder. A randomized, blinded, prospective study.

Front Psychiatry · 2024 · PMC10896889 · PMID 38414497

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marginally significantno p-value reported

However, omega-6 FA administration significantly reduced TRP levels after 6 weeks and marginally significant after 12 weeks.

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borderline significantno p-value reported

Similarly, omega-6 FA increases the KYN/TRP ratio after 6 weeks of supplementation, but after 12 weeks the increase is borderline significant.

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