People living with HIV display increased anti-apolipoprotein A1 auto-antibodies, inflammation, and kynurenine metabolites: a case-control study.

Anti-apoA1 IgG was not associated with FRS, cIMT, or FMD, despite a possible trend with FRS and cIMT in the PLWH ART-treated group ( p = 0.061 and p = 0.083, respectively) ( Table 2 ).

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Across the three groups (healthy volunteers, PLWH ART-treated, and PLWH ART-naïve), we observed a decreasing trend for HDL-C and apoA1 levels, with the lowest levels observed in PLWH ART-naïve ( Table 1 ), while increasing trends were observed for most markers of systemic inflammation measured in negative controls vs. the PLWH group, with a few exceptions.

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