Ribogenesis boosts controlled by HEATR1-MYC interplay promote transition into brain tumour growth.

Interestingly, comparing our human gene dataset (DIOPT 5-15) to that of MacLeod and colleagues following CRISPR knockdown screens in 10 GSC lines (MacLeod et al, 2019 ) by gene set enrichment analysis (GSEA) reveals a highly significant enrichment in genes reported to contribute to GSC fitness (Fig.

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