Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche.

As validation of the TS-MAP approach, GSEA of LC–MS/MS data revealed highly significant enrichment for the SURFME catalogue encompassing 3,319 cell-surface proteins (Additional file 3 : Data File S2), in both surface and endocytosed protein fractions (Fig. 2 C, D , and Additional file 1 : Fig.

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