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Trends in orphan medicinal products approvals in the European Union between 2010-2022.

Orphanet J Rare Dis · 2024 · PMC10900541 · PMID 38413985

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an increasing trendno p-value reported
Non-standard MA’s are less frequent in the non-orphan medicines group but, as in the orphan medicines group, we observe an increasing trend of this type of MA’s over the period studied (Fig. 3 ).

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