Interestingly, NASH was associated with a higher (although only borderline significant) microbiota diversity compared to animals with HFD without NASH (Fig. 4 A), indicating an association of the intestinal microbiota with liver inflammation beyond the HFD.
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Development of non-alcoholic steatohepatitis is associated with gut microbiota but not with oxysterol enzymes CH25H, EBI2, or CYP7B1 in mice.
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