Moreover, the expression of COL3A1 ( P <0.05 ), COL1A1 , and vascular cell adhesion molecule 1 ( VCAM1 ) showed an increasing trend of fibrosis of Orgs-H induced by IL-17A, and was relatively decreased by Exo MSC .
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MSC-derived exosomes attenuate hepatic fibrosis in primary sclerosing cholangitis through inhibition of Th17 differentiation.
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