Feasibility of online managing cancer and living meaningfully (CALM) in Chinese patients with metastatic breast cancer: a pilot randomized control trial.

Although the differences in death anxiety at matched time points post-intervention did not achieve significance in this small pilot randomized controlled trial, we did observe significant between-group differences in several secondary outcome measures, with the patients benefitting significantly from receiving full six sessions of CALM therapy on the following metrics: depression severity, distress level, attachment avoidance and sense of life completion, with the effect size ranging from moderate to large.

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