marginally significantp < 0.001
In line with these results, mosquitoes fed with dsCHIK1 did not show any significant reduction in viral titers after infection with CHIKV, whereas mosquitoes injected with dsCHIK1 showed reduced viral titers in whole bodies two days post-infection and marginally significant reduced titers five days post-infection ( Figures S5 A–S5C, Kruskal-Wallis test on log-transformed viral titers: day 2 p < 0.001; day 5 p = 0.04; Kruskal-Wallis test on prevalence: day 2 p = 0.18; day 5 p = 0.07; see Table S2 for individual comparisons).