One study, including 9895 subjects, showed that elevated AST levels were a risk factor of diabetes (elevated versus normal AST; OR:1.75 [1.32-2.32]), whereas AST within the normal ranges of quartiles 2, 3, and 4 was negatively associated with T2D risk compared with quartile 1 (Q2, Q3, Q4 versus Q1, OR<1, 95% CI <1) ( 25 ), indicating that the association between AST and diabetes risk may be a non-linear trend of initially decreasing followed by an increasing trend.
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Association between liver enzymes and type 2 diabetes: a real-world study.
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