In comparison to baseline values, the results for all 30 SMA patients taken together were highly significant for all subgroups up to the 18–24 months group (Figure 2A ; Table 3 ), whereas the results for SMA type 1 subjects only, probably due to a lower number of cases analyzed, were significant for the 18–24 months group only (Figure 2B ). 3.3.
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Total tau in cerebrospinal fluid detects treatment responders among spinal muscular atrophy types 1-3 patients treated with nusinersen.
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