The expression level of TGF-β after SCI was analyzed by western blotting (WB) and TGF-β showed an increasing trend at three incremental time points as the mice themselves recovered, while the TGF-β level in the M&N group at each time point was significantly lower than the Con group, which showed that cell transplantation reduced the level of fibrosis in SCI (Fig. 3 I, J).
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Combined transplantation of hiPSC-NSC and hMSC ameliorated neuroinflammation and promoted neuroregeneration in acute spinal cord injury.
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