highly significantP = 8.4 × 10 −10
Analyses of differential expression of the genes through the FUMA pipeline 37 recapitulated these findings, indicating highly significant (minimum P = 8.4 × 10 −10 ) upregulation in prenatal brain tissue and downregulation postnatally for the first cluster, and vice versa (minimum P = 1.1 × 10 −11 ) for the second cluster, see Supplementary figure 3 .