Inhibition of <i>Cpeb3</i> ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs and enhances object location memory.

Essential revisions: The reviewers all felt that the topic was important and that going from a ribozyme in an interesting gene to behavior was highly significant.

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While the two-tailed test indicates that the difference is not statistically significant at the conventional alpha level of 0.05, the one-tailed test suggests a marginal significance, with evidence supporting an upregulation of Cpeb3 mRNA expression by OLM training.

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