TCL1-Tg BAFF -/- mice exhibited a decreasing trend in spleen weight up to 9 months of age compared to both TCL1-Tg and TCL1-Tg APRIL -/- mice ( Figure 2C ), along with spleen sizes similar to those observed in BAFF -/- control mouse groups ( Figure 2D ).
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An unappreciated cell survival-independent role for BAFF initiating chronic lymphocytic leukemia.
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