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Tetrahedral DNA loaded siCCR2 restrains M1 macrophage polarization to ameliorate pulmonary fibrosis in chemoradiation-induced murine model.

Mol Ther · 2024 · PMC10928155 · PMID 38273656

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Moreover, slightly decreasing trends of collagen deposition and the number of M1 macrophages were found between day 30 and day 45, as well as a decreasing trend in CCL2 expression at the time points of 15, 30, and 45 days.

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