a numerical trendp = 0.12
However, early relapses (within the first 2 months of adjuvant treatment, n = 17) proved particularly difficult, with a significant reduction in the second PFS (PFS2, HR 1.83, p = 0.029) ( Figure 4 C) and a numerical trend for reduced OS2 (HR 1.77, p = 0.12), compared to relapses that had occurred after 2 months (n = 124).