As concerning FoldX-generated ΔΔG values, those larger than 1.6 kcal/mol should be considered highly significant (2 standard deviations of the FoldX error, 99% confidence interval), but energy variations greater than 0.8 kcal/mol can still be considered reliable (1 standard deviation, 95% confidence interval) [ 66 ].
← all excerpts
Cancer-Related Mutations in the Sam Domains of EphA2 Receptor and Ship2 Lipid Phosphatase: A Computational Study.
1
—
—