At the same time, the trend in rotavirus hospitalizations had a decreasing trend over the same periods in a similar study conducted in another Italian region where vaccination had been introduced as early as 2013 [ 22 ].
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Rates and determinants of Rotavirus vaccine uptake among children in Italy: a cross-sectional study within the 2022 OBVIOUS* project.
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In fact, until 2018 there was an increasing trend of rotavirus gastroenteritis hospitalizations in regions where the vaccination had only been offered since 2017 and vaccination coverage levels were suboptimal [ 21 ].