Supramolecular Chemotherapy: Complexation by Carboxylated Pillar[6]arene for Decreasing Cytotoxicity of Nitrogen Mustard to Normal Cells and Enhancing Its Antitumor Efficiency against Breast Cancer.

1 Of all types of carcinomas, breast cancer is one of the most common malignancies and is reported to have an increasing trend of incidence and mortality, seriously affecting a large number of female patients. 2 The age of patients with breast cancer is also tending toward younger females, and it is hard to implement recovery due to its high ratio of recurrence. 3 , 4 Owing to this, advanced therapeutic regimens are urgently required to boost treatment outcomes.

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