In the present analysis, virologic success rates were significantly lower at weeks 4, 12, and 24 after ART initiation in participants with TB-IRIS compared with those without TB-IRIS, and borderline significant at week 48, probably because of higher baseline HIV-RNA levels observed among those who developed TB-IRIS.
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Incidence and Predictors of Tuberculosis-associated IRIS in People With HIV Treated for Tuberculosis: Findings From Reflate TB2 Randomized Trial.
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