High-content method for mechanosignaling studies using IsoStretcher technology and quantitative Ca<sup>2+</sup> imaging applied to Piezo1 in cardiac HL-1 cells.

Cell Mol Life Sci · 2024 · PMC10940437 · PMID 38485771

Europe PMC DOI

hedged sentence

0.0100

closest p · 0.2× alpha

0.0100

boldest claim

The sentences

highly significantp < 0.01actually significant

Statistical analysis shows a highly significant increase in cellular Ca 2+ oscillation activity caused by treatment with GsMTx4 in cells only activated by stretch (one way ANOVA, p < 0.01) while in spontaneously active cells, GsMTx4 had the significantly opposite effect.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.