When miR-3940-5p inhibitor was transfected into SH-SY5Y cells, the mRNA ( p < 0.05; Figure 2B ) and protein ( p = 0.051; Figure 2C ) levels of PSEN1 were significantly increase, although the increase in protein was marginally significant.
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miR-3940-5p reduces amyloid β production via selectively targeting <i>PSEN1</i>.
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