highly significantp < 0.01
3.5 Serum levels of IL-6, TNF-α, TMAO, and hepatic TMAO in diarrhea with kidney-yang deficiency syndrome mice In Figure 4 , compared with the CN group, the CD group exhibited a significant increase in TNF-α ( p < 0.01) and a highly significant increase in IL-6 ( p < 0.01) in serum.