Image-Based Biological Heart Age Estimation Reveals Differential Aging Patterns Across Cardiac Chambers.

A large population study in the UK Biobank found increasing age‐related increase in myocardial native T1 in men and a decreasing trend in women. 35 A smaller study of the Multi‐Ethnic Study of Atherosclerosis cohort reports positive association of native T1 with increasing age in men, but no significant age trend in women. 35 The age dependency of T2 is less consistent, with some researchers reporting no relationship between T2 and age, 36 while others report a decreasing trend. 37 In our analysis, we used shape and SI‐based radiomics features extracted from bSSFPF short‐axis cine images.

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