Factors influencing JUUL e-cigarette nicotine vapour-induced reward, withdrawal, pharmacokinetics and brain connectivity in rats: sex matters.

Neuropsychopharmacology · 2024 · PMC10948865 · PMID 38057369

Europe PMC DOI

hedged sentence

0.0521

closest p · 1.0× alpha

0.0521

boldest claim

The sentences

trend toward significanceP = 0.0521so close (0.05 < p ≤ 0.1)

While somatic withdrawal did not reach significance in adolescent nicotine females compared to vehicle, they did trend toward significance (t(51) = 1.989, P = 0.0521), supporting previous work in mice that found increased withdrawal in adolescent female mice compared to adults [ 61 ].

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