Calr type 1/like mutation in myelofibrosis is the most prominent predictor of momelotinib drug survival and longevity without transplant.

Blood Cancer J · 2024 · PMC10951334 · PMID 38503764

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0.0800

closest p · 1.6× alpha

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The sentences

of borderline significanceP = 0.08so close (0.05 < p ≤ 0.1)

In univariate analysis, molecular predictors of drug survival included CALR -1 ( P = 0.006) but not ASXL1 ( P = 0.6), SRSF2 ( P = 0.3) or any other myeloid neoplasm-related gene mutation evaluated; unfavorable karyotype was of borderline significance ( P = 0.08).

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