Seroreactivity against lytic, latent and possible cross-reactive EBV antigens appears on average 10 years before MS induced preclinical neuroaxonal damage.

J Neurol Neurosurg Psychiatry · 2024 · PMC10958269 · PMID 37802637

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an increasing trendno p-value reported

13 Similarly, in our previous report on sNfL in successive 5-year periods, 14 average sNfL levels showed an increasing trend starting in specimens obtained 5–10 years before clinical MS onset.

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