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Developmental progression of DNA double-strand break repair deciphered by a single-allele resolution mutation classifier.

Nat Commun · 2024 · PMC10960810 · PMID 38521791

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an overall trendno p-value reported
As an overall trend, mutant alleles accumulated progressively in the Maternal-F lineage until virtually no WT alleles remained, while in Paternal-F lineage, even at the endpoint of adulthood, approximately 60% of WT alleles persisted, in line with our single time point experiments (Fig. 4a, d , Supplementary Fig.

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