We found similar densities of OPCs and oligodendrocytes in both regions with a slight trend towards fewer OPCs in the cortex ( Fig. 2 J ), suggesting that SRF is not necessary for oligodendrocyte maturation or viability.
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SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination.
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2 E ), but this result did not achieve significance in the optic nerve ( SI Appendix , Fig.