Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease.

Additionally, there was a decreasing trend in the levels of mt-Nd2 and mt-Nd4 genes in Jmjd1a HY/HY mice compared to Jmjd1a +/+ mice after cold exposure ( Figure 1 H).

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Female mice also showed an increasing trend in BAT and gWAT weights ( Figures 6 H, S8 H, and S8I).

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