Natural Killer Cell Dysfunction in Premenopausal <i>BRCA1</i> Mutation Carriers: A Potential Mechanism for Ovarian Carcinogenesis.

Overnight co-culture with progesterone (24 h) induced a highly significant reduction in NK cell cytotoxicity of tumor targets at differing concentrations (10 μM vs. 0.1 μM progesterone; n = 13; p = 0.0038; Figure 1 f).

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