The Autism Spectrum Disorder and Its Possible Origins in Pregnancy.

In addition to the aforementioned malformations, genetic factors have been identified as highly significant in the etiology of ASD, due to the high heritability of the disease and the association with fragile X syndrome (FXS), Down syndrome, Prader–Willi syndrome (PWS), genetic microdeletions, and single nucleotide polimorphisms and mutations [ 16 , 17 , 18 , 19 , 20 ].

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