Constitutional <i>BRCA1</i> and <i>MGMT</i> Methylation Are Significant Risk Factors for Triple-Negative Breast Cancer and High-Grade Serous Ovarian Cancer in Saudi Women.

Compared to the controls, our findings indicate a highly significant association between BRCA1 methylation and HGSOC ( p = 0.001 OR = 3.25, 95% CI = 1.58–6.68) ( Table 2 A), but only a marginally significant association between MGMT methylation and HGSOC ( p = 0.054, OR = 2.13, 95% CI = 0.98–4.62) ( Table 2 B). 2.6.

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