Barely Significant
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HFE Mutations in Neurodegenerative Disease as a Model of Hormesis.

Int J Mol Sci · 2024 · PMC10970347 · PMID 38542306

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highly significantno p-value reported
These small studies do not provide conclusive evidence that C282Y HFE is a highly significant disease modifier, but the increased prevalence of AD in those who also carry TF C2, which is associated with increased redox-active iron levels, suggests that increased iron is a likely risk factor for AD.

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