In a study of 47 patients with definite stent thrombosis (90% of whom had the index PCI for ACS), impaired fibrinolysis as measured by rate of increase in D-dimer levels (marker of fibrin degradation) was the strongest independent predictor of stent thrombosis along with clot permeability and stent length, while vessel size and markers of platelet activation/platelet count did not achieve significance [29] .
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