PQR309, a dual PI3K/mTOR inhibitor, synergizes with gemcitabine by impairing the GSK-3β and STAT3/HSP60 signaling pathways to treat nasopharyngeal carcinoma.

Cell Death Dis · 2024 · PMC10981756 · PMID 38555280

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highly significantno p-value reported

A highly significant inhibition of xenograft growth under treatment by the drug combination was observed (Fig. 5A–C, F–H ).

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