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Clinical characteristics and antimicrobial therapy of healthcare-associated carbapenem-non-susceptible gram-negative bacterial meningitis: a 16-year retrospective cohort study.

BMC Infect Dis · 2024 · PMC10985894 · PMID 38566040

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a decreasing trendno p-value reported
Due to vaccination programs, community-acquired meningitis presents a decreasing trend [ 2 ].

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an increasing trendno p-value reported
pneumoniae isolated from the cerebrospinal fluid (CSF) to meropenem show an increasing trend with rates of 85.6% and 64.1% in 2018, respectively, both of which were much higher than those isolated from other specimens (blood, urine, and lower respiratory tract) [ 8 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.