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Trends for opioid prescribing and the impact of the COVID-19 pandemic in patients with rheumatic and musculoskeletal diseases between 2006 and 2021.

Rheumatology (Oxford) · 2024 · PMC10986805 · PMID 37432340

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a decreasing trendno p-value reported
PsA had a decreasing-to-flat curve (0.0010; 95% CI: 0.0006, 0.0015) pre-pandemic, which changed by −0.003 (95% CI: −0.006, −0.0003) during the pandemic, resulting in a decreasing trend.

also in 47,180 other papers

an increasing trendno p-value reported
The UK has also shown an increasing trend of opioid prescribing, including for non-cancer chronic pain [ 3 , 4 ].

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.