PsA had a decreasing-to-flat curve (0.0010; 95% CI: 0.0006, 0.0015) pre-pandemic, which changed by −0.003 (95% CI: −0.006, −0.0003) during the pandemic, resulting in a decreasing trend.
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Trends for opioid prescribing and the impact of the COVID-19 pandemic in patients with rheumatic and musculoskeletal diseases between 2006 and 2021.
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The UK has also shown an increasing trend of opioid prescribing, including for non-cancer chronic pain [ 3 , 4 ].