To focus specifically on motifs that were enriched in CDR3s with highly significant clonal expansion in the APOB-reactive compartment as compared to non-reactive control, we calculated the relative abundances of AIM + and AIM − CDR3s in each expanded group and calculated their log 2 fold change.
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Identification of apolipoprotein B-reactive CDR3 motifs allows tracking of atherosclerosis-related memory CD4<sup>+</sup>T cells in multiple donors.
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